Zhejiang Tasln Biopharma Co.,Ltd
We are professional supplier of Semaglutide,Tirzepatide,Retatrutide,GHK-CU,Linaclotide,Cagrilintide,Eptifibatide.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
Product Description
Eptifibatide is a synthetic cyclic heptapeptide derived from the venom of the southeastern pygmy rattlesnake (Sistrurus miliarus barbourin). It acts as a selective and reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, which is the final common pathway for platelet aggregation.
By binding to the GP IIb/IIIa receptor, eptifibatide prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands to platelets, thereby inhibiting platelet aggregation in a dose- and concentration-dependent manner. The drug has a rapid onset of action and a short plasma half-life of approximately 2.5 hours, allowing for quick recovery of platelet function after discontinuation.
Eptifibatide is indicated for the treatment of patients with acute coronary syndrome (unstable angina/non-ST-segment elevation myocardial infarction), including those receiving medical treatment or undergoing percutaneous coronary intervention (PCI). It is also indicated for patients undergoing PCI, including those receiving intracoronary stent placement, to reduce the risk of death, new myocardial infarction, or the need for urgent intervention.
Key Features:
Selective GP IIb/IIIa receptor antagonist
Reversible and short-acting (half-life ~2.5 hours)
Rapid onset of action
Indicated for ACS and PCI patients
FDA-approved therapy (Integrilin®)
Manufactured under cGMP standards
Clinical Use:
Administered as an intravenous bolus followed by continuous infusion
Used in combination with aspirin and heparin
Reduces ischemic complications in ACS and PCI patients
Specifications:
| Parameter | Specification |
|---|---|
| Purity | ≥98% (≥99% available) |
| CAS No. | 148031-34-9 |
| Molecular Formula | C₃₅H₄₉N₁₁O₉S₂ |
| Molecular Weight | ~832.0 g/mol |
| Peptide Sequence | Mpa-Har-Gly-Asp-Trp-Pro-Cys-NH₂ (cyclic disulfide bridge) |
| Storage | 2-8°C, dry, protected from light |
| Shelf Life | 24 months |
Applications:
Acute coronary syndrome (ACS) research
Percutaneous coronary intervention (PCI) studies
Platelet aggregation inhibition research
Cardiovascular pharmacology
Antithrombotic drug development
Why Choose Us:
cGMP certified manufacturing
≥98-99% purity by HPLC
Comprehensive documentation (COA, stability data, DMF)
24-month shelf life
Reliable global supply with temperature-controlled shipping
Documentation Available:
Certificate of Analysis (COA)
Stability study data (24 months)
GMP statement
DMF (available upon request)
Contact Us
For pricing, DMF status, or sample requests, please contact our sales team.
